- Description
Specifications
Description: | |||||
Due to extensive developments in liposome technology in the recent years, a number of liposome-based drug formulations are available in the clinic market and many products are undergoing different clinical trials. Among them, the liposomes for Adriamycin are Doxil®, Myocet®, DaunoXome®; for Amphotericin B are Abelcet®, Ambisome®, Amphotec®,for Irinotecan is Onivyde®; the micelle for Paclitaxel are Cynviloq™, Apealea®, Genexol-PM®; the lipid complex for siRNA is ONPATTRO®. | |||||
Application: | |||||
Liposome preparation![]() ![]() ![]() ![]() |
|||||
Formulation: | |||||
Doxil® Adriamycin/mL: HSPC: CHOL: DSPE-mPEG2000=2mg: 9.58mg: 3.19mg: 3.19mg; Excipients: Ammonia Sulfate 2mg Histidine 1.55mg Sucrose 94mg Ambisome® Amphotericin B: HSPC: CHOL: DSPG=50mg: 213mg: 52mg: 84mg; Excipients: α-Tocopherol 0.64mg Disodium succinate hexahydrate 27mg Sucrose 900mg Water 12mL Abelcet® Amphotericin B/mL: DMPC: DMPG=5.0mg: 3.4mg: 1.5mg; Excipients: Sodium Chloride: 9.0mg Amphotec® Amphotericin B: Cholesteryl sodium sulfate: Trometamol =50mg: 26.4mg: 5.64mg; Excipients: Disodium edetate 0.372mg Lactose Monohydrate 950mg Water10ml Genexol-PM® Paclitaxel: mPEG-PLA=30mg: 150mg Abraxane® Paclitaxel: Human Albumin=100mg: 900mg |
|||||
Specifications | |||||
Name | Description | Purity | |||
DSPE-mPEG2000 | Methoxypolyethylene glycol DSPE (1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine) | ≥99.0% | |||
HSPC | L-α-phosphatidylcholine, hydro genated (Soy) | ≥99.0% | |||
DSPG | 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, sodium salt | ≥99.0% | |||
DSPC | 1,2-Distearoyl-sn-glycero-3-phosphocholine | ≥99.0% | |||
DMPC | 1,2-dimyristoyl-sn-glycero-3-phosphocholine | ≥99.0% | |||
DMPG | 1,2-dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) | ≥99.0% | |||
CHO | Cholesterol | ≥99.0% | |||
Cholesteryl Sulfate | Cholesteryl sodium sulfate | ≥99.0% | |||
PEG-b-PLA | Monomethoxy-Poly(ethylene glycol)-block-poly(d,l-lactic acid) | Quote | |||
Adriamycin | Active ingradient in Doxil®, Myocet®, DaunoXome® | ≥99.0% | |||
Paclitaxel | Active ingradient in Abelcet®, Ambisome®, Amphotec® | ≥99.0% | |||
Amphotericin B | Active ingradient in Cynviloq™, Apealea®, Genexol-PM® | ≥99.0% | |||
Genizer Liposome Extruder System |
|||||
Catalog No. | Thermo-control | Power mode | Maximum pressure | ||
Hand Extruder | HandExtruder-1mL | None | Hand Drive | 150 psi | |
HandExtruder-1mL-RT | Jacketed | Hand Drive | 150 psi | ||
Jacketed Extruder | GJE-10mL | Jacketed | Compressed Gas | 3000psi | |
GJE-100mL | Jacketed | Compressed Gas | 3000psi | ||
GJE-800mL | Jacketed | Compressed Gas | 3000psi | ||
GJE-3000mL | Jacketed | Compressed Gas | 3000psi | ||
GJE-10000mL | Jacketed | Compressed Gas | 3000psi | ||
Online Extruder | GOE-25mL | Jacketed | Online Pump | 6000psi | |
GOE-200mL | Jacketed | Online Pump | 6000psi | ||
GOE-1000mL | Jacketed | Online Pump | 6000psi | ||
GOE-8L | Jacketed | Online Pump | 6000psi | ||
GOE-20L | Jacketed | Online Pump | 6000psi | ||
Multi Extruder | GOE-8L*2 | Jacketed | Online Pump | 6000psi | |
GOE-8L*4 | Jacketed | Online Pump | 6000psi | ||
GOE-8L*8 | Jacketed | Online Pump | 6000psi | ||